MD 381 Travel Info
2025-10-25
Roadnow
Maryland Route 381 (Brandywine Road) is a state highway in Charles County and Prince George's County. It begins by branching off of MD 231 (Prince Frederick Road) in eastern Charles County and heads north for 1.38 miles (2.22 km) before crossing into the south-eastern tip of Prince George's County. In Prince George's County, it continues onwards through mostly rural ... more
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