South Carolina Highway 83 (SC 83) is a primary state highway in the U.S. state of South Carolina. It connects the communities of eastern Marlboro County with Maxton, North Carolina.

SC 83 is a two-lane rural highway that traverses 4.7 miles (7.6 km), north of Clio to the North Carolina state line.

Established in 1938 as a renumbering of SC 68 and match NC 83; no changes since.

The entire route is in Marlboro County.