Major Cities along US 81 (SD) 2025-11-11 Roadnow US 81 (SD) Major Cities MAP Yankton MAP Tabor MAP Utica MAP Irene MAP Menno MAP Freeman MAP Marion MAP Bridgewater MAP Humboldt MAP Canistota MAP Salem MAP Montrose MAP Spencer MAP Canova MAP Winfred MAP Howard MAP Madison MAP Ramona MAP Nunda MAP Arlington MAP Oldham MAP Sinai MAP Brookings MAP Volga MAP Lake Norden MAP Estelline MAP Hayti MAP Castlewood MAP Watertown MAP Summit MAP Sisseton
