South Carolina Highway 768 (SC 768) is a primary state highway in the U.S. state of South Carolina. It serves to connect businesses along Shop Road to nearby state highways.

SC 768 is an urban highway that zig-zags from SC 48 to US 76/378 for 4.8 miles (7.7 km). The main stretch is Shop Road, where it is a four-lane divided highway; while Beltline Boulevard and Pineview Road are a two-lane with medium. Signage along the route is poorly marked.

The first SC 768 appeared from 1942-1948 as a spur off US 76, from Marion 4 miles (6.4 km) to Pitch Pot Swamp. It was downgraded to secondary status.

The current SC 768 was established between 1980–82, as a new primary routing; which has changed little since.

The entire route is in Columbia, Richland County.