County Route 539, abbreviated CR 539, is a county highway in the U.S. state of New Jersey. The highway extends 53.49 miles (86.08 km) from Main Street (U.S. Route 9) in Tuckerton to U.S. Route 130 in Cranbury Township. However, signage on CR 539 suggests that it crosses U.S. 130 and terminates at the intersection with CR 535.

CR 539 begins at an intersection with US 9 in Tuckerton, Ocean County, heading north on two-lane undivided North Green Street. South of US 9, the road continues as CR 603. The route passes through residential areas as it becomes the border between Little Egg Harbor Township to the west and Tuckerton to the east before fully entering Little Egg Harbor Township. CR 539 heads through decreasing residential development as it heads into the densely forested Pine Barrens and intersects CR 602 prior to an interchange with the Garden State Parkway. Following this interchange, the route comes to the CR 606 junction and passes through the rural Pine Barrens for several miles. Upon crossing into Stafford Township, the road passes through the small residential community of Warren Grove, where it intersects CR 608. From here, CR 539 passes through more forest, intersecting CR 610 before becoming Warren Grove-Whiting Road entering Barnegat Township and crossing Route 72/CR 532.

After this intersection, the road continues north and passes through Lacey Township as Cedar Bridge-Whiting Road before entering Manchester Township and becoming Roosevelt City Road. The route passes near a few wooded areas of homes before running through more forest and passing housing developments and businesses in the community of Whiting. Here, CR 539 intersects CR 530 and forms a brief concurrency with that route, passing businesses as it comes to the Route 70 junction. At this point, CR 530 turns west along Route 70 and CR 539 heads northwest into more of the Pine Barrens on Whiting-New Egypt Road, becoming Pinehurst Road at the CR 14 junction. The route briefly passes through Jackson Township before entering Plumsted Township, where the road turns northwest and north through forested areas of the Fort Dix Military Reservation. After leaving the Fort Dix grounds, CR 539 enters a mix of farms and woods with a few homes and businesses, heading northwest and crossing CR 640. Following this junction, the route enters more wooded areas of residential development, passing New Egypt Speedway before crossing CR 528. The passes more rural areas of homes before becoming Hornerstown Road and reaching an intersection with CR 537.

Upon crossing CR 537, CR 539 enters Upper Freehold Township in Monmouth County and intersects CR 27, at which point the road becomes Trenton-Forked River Road and heads through agricultural areas with some homes, crossing another section of CR 27. The route heads through more areas of farms, woods, and residences, where it turns west onto Davis-Allentown Road and runs northwest through more rural areas. CR 539 enters Allentown, where it becomes High Street and passes through residential areas before intersecting CR 524. CR 539 forms a concurrency with CR 524, with the two routes continuing northeast along Main Street to a short overlap with CR 526. The road leaves Allentown for Upper Freehold Township and enters farmland as it intersects CR 526 Spur. A short distance later, CR 524/CR 539 reaches an interchange with I-195.

At this point, the name of the road becomes Old York Road and it forms the border between Robbinsville Township, Mercer County to the west and Upper Freehold Township, Monmouth County to the east briefly before CR 524 splits from CR 539 by turning east along New Canton-Stone Tavern Road. CR 539 continues northeast past a mix of farms and residential subdivisions before passing through more agricultural surroundings. The road briefly turns east and runs through a wooded part of Millstone Township, Monmouth County.

After a turn to the north, CR 539 enters East Windsor Township in Mercer County and passes farms with some homes, intersecting CR 630 before passing over the New Jersey Turnpike (I-95). Following this, the road passes through residential subdivisions before entering Hightstown. CR 539 becomes Main Street at this point and passes homes, with CR 571 joining the route from the east. Upon reaching the commercial downtown of Hightstown, Route 33 joins CR 539/CR 571 on Main Street before CR 571 turns to the west along Stockton Street. After crossing the Rocky Brook, Route 33 splits from CR 539 by heading to the east and CR 539 continues past more homes, intersecting CR 633. The road heads back into East Windsor Township and becomes Hightstown Road as it runs through farmland and passes under Route 133. The road passes near housing developments before crossing the Millstone River into Cranbury Township, Middlesex County in wooded areas. CR 539 reaches its northern terminus at an intersection with US 130 a short distance later, even though signage continues the route north along CR 685 to CR 535.

When the 500-series county routes were first designated, CR 539 traveled west from Hightstown to Princeton on Stockton Street, Princeton–Hightstown Road, and Washington Road, the route of present-day CR 571. It became CR 571 by 1976.

Two special routes of CR 539 existed at the creation of the 500-series county routes. County Route 539 Spur ran from Warren Grove to Waretown. The road today is now Ocean County Route 610 from CR 539 to Route 72, and CR 532 from Route 72 to its current end at US 9 (CR 532 at the time ran on what is now CR 554). This designation was removed by 1961. County Route 539 Alternate followed what is now CR 526 from Allentown to Princeton Junction. It was renumbered as a western extension of CR 526 by 1956.

Parts of CR 539 in Monmouth County were planned to be a part of Route 37 which would have ran from Trenton to Seaside Heights. The section of the road which was actually built as a state highway was between CR 537 and Burlington Path Road (CR 27) in Upper Freehold. Though this section is no longer state-maintained, this section of CR 539 still has a wide right-of-way, wide shoulders, and an old bridge from 1940 with "State Highway Route 37" engraved on the ends.