US 221 (SC) Intersections with interstate highways 2025-10-28 Roadnow US 221 (SC) Intersections with interstate highways MAP I-85, near Spartanburg, New York map • nearbyMAP I-26, near Roebuck, New York map • nearbyMAP I-385SC, near Laurens, New York map • nearbyMAP I-26, near Roebuck, New York map • nearbyMAP I-585SC, near Spartanburg, New York map • nearbyMAP I-585SC map • nearbyMAP I-585SC, near Spartanburg, New York map • nearby
