State Route 28 (SR 28) is a 16.2-mile (26.1 km) road that runs along the northeastern shore of Lake Tahoe. The road has been designated as the north piece of the Lake Tahoe–Eastshore Drive Scenic Byway as part of the National Scenic Byway program. (The byway continues south on US 50 to Stateline.) The highway is one of three Nevada state routes to continue into California with the same number, the others being State Route 88 and State Route 266.

The highway serves Douglas County and Washoe County as well as a rural part of Carson City

SR 28 begins at U.S. Route 50 in Douglas County, Nevada. It heads north from here, forming part of the boundary of Lake Tahoe – Nevada State Park until crossing into Carson City. The highway then enters Washoe County and where the highway enters Humboldt-Toiyabe National Forest. It then turns northwest, running through Incline Village. In western Incline Village, SR 28 junctions with State Route 431, which is a direct link to Reno to the northeast. Just short of the California state line, it turns south to run parallel to the line and finally crosses into California at Crystal Bay. The road continues west of the California border as State Route 28.

The Route 28 corridor has been used for flumes in the timber industry since 1880. The highway gained fame for many years as the location of the Ponderosa Ranch, filming location of the television series Bonanza.