Minnesota State Highway 264 is a highway in southwest Minnesota, which runs from its intersection with Nobles County Road 21 (2nd Avenue) in Round Lake and continues north to its northern terminus at its interchange with Interstate 90 and Jackson County Road 1, six miles east of Worthington.

The route is 7.3 miles (11.7 km) in length.

Highway 264 serves as a north–south route in southwest Minnesota between Round Lake and Interstate 90.

The route runs along the county line for Nobles and Jackson counties for most of its length.

Highway 264 follows Amy Avenue and Main Street in Round Lake.

The route is legally defined as Route 264 in the Minnesota Statutes.

Highway 264 was authorized on July 1, 1949.

The route was paved in the mid-1950s.

Nearly all of the route is on the county line between Nobles and Jackson counties.

*Mn/DOT. Nobles County General Highway Map. Accessed May 2, 2010. *Mn/DOT. Jackson County General Highway Map. Accessed May 2, 2010.