State Route 273 (SR 273) is a west-east state highway located in the southwestern part of the U.S. state of Georgia. Its route lies within Early and Miller counties.

There is no section of SR 273 that is included as a part of the National Highway System, a system of routes determined to be the most important for the nation's economy, mobility and defense.

SR 273 begins at an intersection with SR 273 Spur and SR 370 southwest of Cedar Springs. The route heads northeast to Cedar Springs and then heads east to an intersection with SR 39 just before entering Miller County. It then heads east-southeast to meet its eastern terminus, an intersection with SR 91 southwest of Colquitt. Here, the roadway continues as Cypress Creek Road.

SR 273 was established in 1950 along an alignment from US 84/SR 38 in Jakin, Georgia northeast to SR 39 near the unincorporated community of Killarney. By 1969, SR 273 was moved to the same alignment as it runs today.

State Route 273 Spur (SR 273 Spur) exists entirely within the west central part of Early County.

There is no section of SR 273 Spur that is included as a part of the National Highway System, a system of routes determined to be the most important for the nation's economy, mobility and defense.

It begins just east of the Chattahoochee River. The highway heads nearly due east until it meets its eastern terminus, an intersection with the SR 273 mainline and SR 370 southwest of Cedar Springs.

The road that is now SR 273 Spur was established in 1968 as SR 363 Spur, when the road that is now SR 370 was established as SR 363. By 1998, SR 363 Spur was redesignated as SR 273 Spur.

The entire route is in Early County.