Arkansas Highway 349 is the name of multiple state highways in Arkansas.

Arkansas Highway 349 is a state highway of 5.5 miles (8.9 km) that runs in Craighead County.

AR 349 runs from US 49 north across AR 226 to terminate at AR 18/AR 91 in Herman.

Arkansas Highway 349 is a state highway of 2.4 miles (3.9 km) that runs in Lawrence County.

AR 349 serves as a connector between AR 228 an AR 230 in rural Lawrence County.