Vermont Route 12 is a north-south state highway in Vermont that runs from Weathersfield to Morrisville.

Route 12 begins at the New Hampshire state line on the Connecticut River in the town of Weathersfield. It continues north along the west bank of the Connecticut River, overlapped with U.S. Route 5, until Hartland. It then heads northwest to Woodstock and then north through Montpelier to end at Vermont Route 100 in Morrisville. Vermont Route 12 runs parallel to Interstate 89 from the Woodstock/Hartford vicinity to Montpelier.

Vermont Route 12A is a state highway in central Vermont, United States. It provides an alternate to VT 12 between Randolph and Northfield, via Braintree, Granville and Roxbury.

The road currently used by Vermont Route 12A was originally designated New England Interstate Route 12A in 1922 as part of the New England Interstate Route System and existed as such until it was replaced by a different system in 1926.