Route 116 is a numbered State Highway running 26.3 miles (42.3 km) in Rhode Island.

Route 116 takes the following route through the State:

Route 116 is a major corridor in Lincoln, Cumberland and parts of Smithfield.

The interchange between Route 116 and Route 146 was the first cloverleaf interchange to be constructed in the state. As of July 2005 it was in the process of being reconstructed.