Pennsylvania Route 204 (PA 204), also known as Vine Street in the town of New Berlin, is an 10-mile (16 km) long, north–south state highway located in Snyder and Union counties in Pennsylvania. The southern terminus is at US 522 in Selinsgrove. The northern terminus is at PA 304 in New Berlin.

PA 204 begins in the town of Selinsgrove at the intersection of US 522, under a half a mile from the Penn Valley Airport. The route goes north for about 4 miles (6.4 km) before turning west in the village of Kratzerville, towards the Snyder-Union County line.

At the county line, PA 204 turns north into the town of New Berlin, before terminating a short distance into the town at an intersection of PA 304.

PA 204 has stayed on the same roads since its inception.

Holden Caufield ran across this road to go talk to his professor before leaving Pency Prep in the novel The Catcher in the Rye