Maryland Route 287 (MD 287) is a state highway in the U.S. state of Maryland. Known for much of its length as Sandtown Road, the state highway runs 2.88 miles (4.63 km) from MD 313 in Goldsboro east to the Delaware state line, where the highway continues east as Delaware Route 10 (DE 10). MD 287 was constructed in the early 1930s.

MD 287 begins at an intersection with MD 313 on the northwest edge of Goldsboro. MD 313 heads south into the town as Oldtown Road and west as Goldsboro Road. MD 287 heads east as Old Line Road along the northern edge of Goldsboro. After intersecting MD 311 (Main Street) and crossing an unused railroad grade owned by the Maryland Department of Transportation, the state highway's name changes to Sandtown Road and it heads east through farmland, crossing Broadway Branch and the upper part of the Choptank River. MD 287 reaches its eastern terminus at the Delaware state line, where the highway continues east as DE 10 (Willow Grove Road) toward Dover.

MD 287 was constructed starting in 1930 and completed by 1933.

The entire route is in Caroline County.