State Route 354 (SR 354) is a short, arc-shaped state highway entirely in Harris County. It starts out in an easterly direction, then it turns southerly, and finally, in a southwesterly direction.

From its western terminus at SR 18 southwest of the town of Pine Mountain, the route travels east, intersecting US 27/SR 1 in Pine Mountain. The route then turns south, ascending the peak of Pine Mountain. On top of the mountain, SR 190 passes over the route on a historic bridge built by the Civilian Conservation Corps.[citation needed] The route then descends the mountain into the valley below, reaching its eastern terminus at SR 116 in the town of Pine Mountain Valley. The route serves as a connector and access road to traffic visiting F.D. Roosevelt State Park.

The entire route is in Harris County.