Wyoming Highway 241 is a state road in Lincoln County, Wyoming that parallels US 89 for a short distance just south of Afton.

Wyoming Highway 241 begins its southern end at US Route 89 in Smoot and from there parallels US 89 which lies east of Highway 241. WYO 241 heads north 4.27 miles and ends at Wyoming Highway 236 near its east end with US 89; located just south of Afton.

The entire route is in Lincoln County.