Major Cities along US 281 (KS) 2024-10-06 Roadnow US 281 (KS) Major Cities MAP Hardtner MAP Kiowa MAP Medicine Lodge MAP Sawyer MAP Isabel MAP Pratt MAP Iuka MAP Turon MAP Saint John MAP Great Bend MAP Hudson MAP Ellinwood MAP Hoisington MAP Olmitz MAP Russell MAP Otis MAP Pawnee Rock MAP Waldo MAP Paradise MAP Luray MAP Osborne MAP Portis MAP Smith Center MAP Gaylord MAP Lebanon MAP Red Cloud