Arkansas Highway 60 (AR 60, Ark. 60, Hwy. 60) is a designation for five state highways in Arkansas. One segment of 54.19 miles (87.21 km) runs from Highway 28 in Plainview east to US Route 65 Business (US 65B) in Conway. A segment in western Logan County of 2.64 miles (4.25 km) begins at the Old Highway 10 at the Sebastian County line and runs east to Highway 10. A third segment of 10.80 miles (17.38 km) begins at Highway 252 and runs east to Highway 41 at Peter Pender. A fourth segment runs 1.34 miles (2.16 km) from US 64 and runs across Interstate 40/Interstate 540 (I-40/I-540) to Highway 282. A fifth route of 2.34 miles (3.77 km) begins at Highway 282 near Rudy and runs east to County Road 23 (CR 23).

Highway 60 begins at U.S. Route 65 Business in Conway. It runs west for 1.5 miles (2.4 km) and intersects with spur route 60. It continues west for 5.5 miles (8.9 km) until it reaches the County Line at the overpass of Toad Suck Ferry Lock and Dam. Highway 60 then continues to run west for 7.7 miles (12.4 km) and meets with State Highway 113. It continues west for 3.8 miles (6.1 km) with Highway 113 and meets the northern terminus of Highway 216 in Houston.

0.1 miles (0.16 km) west of Highway 216, Highway 113 splits off from highway 60. Highway 60 then runs west for 6.5 miles (10.5 km) to Perryville where it intersects with Highway 9. Both highways follow the same path south in Perryville for 0.3 miles (0.48 km) where they diverge. Highway 60 then runs west for 10.8 Miles to where it intersects with the northern terminus of Highway 177. It then runs west for another 10.1 miles (16.3 km) till it intersects with Arkansas Highway 7. It then crosses Highway 7 and runs west 1.6 miles (2.6 km) to the county line.

From the county line, Highway 60 runs west 7.0 miles (11.3 km) to terminate at Highway 28. Along this route it passes by Nimrod Lake.

Arkansas Highway 60 is a state highway of 1.34 miles (2.16 km) in Crawford County. The route runs north from US 64 over Interstate 40 to terminate at AR 282