Maryland Route 223 (MD 223) is a state highway in the U.S. state of Maryland. The state highway runs 12.65 miles (20.36 km) from Livingston Road in Piscataway north to Mellwood Road in Melwood. MD 223 passes through suburban areas of southern Prince George's County, including the community of Woodyard south of Andrews Air Force Base between MD 5 in Clinton and MD 4 in Melwood.

MD 223 begins at an intersection with county-maintained Livingston Road in Piscataway. Livingston Road, which was formerly part of MD 224, heads south toward Accokeek and north toward Fort Washington. The state highway heads northeast as two-lane Floral Park Road. MD 223 turns north onto Piscataway Road at the four-way intersection with that highway; Floral Park Road continues east toward Brandywine. The state highway crosses Piscataway Creek and continues northeast through a mix of forest and residential subdivisions. MD 223 intersects Tippett Road, which heads south toward the historic home Wyoming, next to Washington Executive Airport. The state highway expands to a four-lane undivided highway as it enters Clinton, where the highway passes Surrattsville High School and the Surratt House Museum and intersects the old alignment of MD 5, which heads north as Old Branch Avenue and south as Brandywine Road. MD 223 enters a commercial area and expands to a divided highway around its single-point urban interchange with MD 5 (Branch Avenue).

MD 223 continues east from MD 5 as two-lane Woodyard Road. The state highway intersects Dangerfield Road and Old Alexandria Ferry Road in the hamlet of Coles Corner. MD 223 continues east to the community of Woodyard, where the highway passes the historic home His Lordship's Kindness and cross Piscataway Creek again. MD 223 turns north to continue on Woodyard Road at its intersection with Rosaryville Road, which heads southeast toward the village of Rosaryville and Rosaryville State Park. The state highway gradually curves to the north through the community of Melwood. MD 223 expands to a four-lane divided highway right before its intersection with the old alignment of MD 4, Marlboro Pike. The state highway, now named Mellwood Road, meets MD 4 (Pennsylvania Avenue) at a partial cloverleaf interchange, then immediately intersects Old Marlboro Pike, which leads east to the historic home Melwood Park. MD 223 reaches its northern terminus immediately to the north when the divided highway rapidly reduces to a very narrow, forest-lined, two-lane county highway.

The entire route is in Prince George's County.

MD 223A is the designation for an unnamed 0.10-mile (0.16 km) section of old alignment of MD 223 between the Piscataway Road – Floral Park Road intersection and Piscataway Creek in Piscataway.