State Route 682 (SR 682, OH 682) is a north–south state highway in the southeastern portion of the U.S. state of Ohio. The southern terminus of State Route 682 is at a trumpet interchange with the triplex of U.S. Route 33, U.S. Route 50 and State Route 32 triplex in Athens. Its northern terminus is at State Route 13 in the village of Chauncey, Ohio.

State Route 682, which debuted in the late 1930s, exists entirely within Athens County, and serves as a southern bypass for the city of Athens. It passes near the main campus of Ohio University.

The entirety of State Route 682 is located in the central part of Athens County. It is not a component of the National Highway System, a system of highways deemed most important for the economy, mobility and defense of the nation.

When it was established in 1937, State Route 682 ran from the State Route 56 junction just southwest of Athens to the point where State Route 682 currently meets the connector road to U.S. Route 33 just southwest of Chauncey, and northwest of where State Route 682 crosses over the Hocking River. At the time, this was where State Route 682 met the predecessor to what would later become the first routing of U.S. Route 33 through this area, known at the time as State Route 31. By 1961, a new stretch of expressway opened to the south of Chauncey. A re-routing of U.S. Route 33 out of Chauncey and onto this new expressway resulted in an extension of State Route 682 northeasterly into the village along the former two-lane routing of U.S. Route 33 up to the state highway's current northern terminus at the State Route 13 junction (the remainder of the old 33 became an extension for State Route 13). By 1969, State Route 682 was extended southeasterly through Athens to its current southern terminus at the triplex of U.S. Route 33, U.S. Route 50 and State Route 32.

The entire route is in Athens County.