US 221 (SC) Intersections with interstate highways 2026-01-03 Roadnow US 221 (SC) Intersections with interstate highways MAP I-85, near Spartanburg, Florida map • nearbyMAP I-26, near Roebuck, Florida map • nearbyMAP I-385SC, near Laurens, Florida map • nearbyMAP I-26, near Roebuck, Florida map • nearbyMAP I-585SC, near Spartanburg, Florida map • nearbyMAP I-585SC map • nearbyMAP I-585SC, near Spartanburg, Florida map • nearby
