US 221 (SC) Intersections with interstate highways 2026-10-06 Roadnow US 221 (SC) Intersections with interstate highways MAP I-85, near Spartanburg, District of Columbia map • nearbyMAP I-26, near Roebuck, District of Columbia map • nearbyMAP I-385SC, near Laurens, District of Columbia map • nearbyMAP I-26, near Roebuck, District of Columbia map • nearbyMAP I-585SC, near Spartanburg, District of Columbia map • nearbyMAP I-585SC map • nearbyMAP I-585SC, near Spartanburg, District of Columbia map • nearby
