State Route 245 is a north–south highway that runs from near Exeter to near Kings Canyon National Park, connecting State Route 198 in Tulare County to State Route 180 in Fresno County. It runs through the city of Woodlake and the small unincorporated towns of Elderwood, Badger, and Pinehurst. Roughly 95% of its 42-mile (68 km) length traverses rural areas. It was formerly numbered State Route 69. North of Avenue 364 (Tulare County), State Route 245 is synonymous with Millwood Drive.

The route begins at State Route 198 amid Tulare County. It then heads north and intersects State Route 216 in Woodlake and County Route J27 amid farmland in the county. The route continues to meet State Route 201 in Elderwood. After several miles through Tulare County, it crosses into Fresno County, where it meets its north end at State Route 180.

The route was defined in 1963 from Interstate 5 to SR 60 in the Los Angeles area. This route was deleted in 1965 and was replaced the former deleted State Route 69 in 1972.