State Route 216 (SR 216) is a state highway in the U.S. state of California in Tulare County. It is a loop of Route 198, running from Visalia to Woodlake.

The route begins at State Route 198 in Visalia with an interchange. It then continues to Ivanhoe, where it meets County Route J34. As it continues through Tulare County, it enters Woodlake, where it meets State Route 245. It then meets County Route J21 before meeting its north end at State Route 198.

Except where prefixed with a letter, postmiles were measured on the road as it was in 1964, and do not necessarily reflect current mileage. The entire route is in Tulare County.