State Route 245 or SR-245 is a 3-mile (4.8 km) long route that serves as a bypass to the northeast of Greenville between State Route 10 and State Route 185.

The southern terminus of SR-245 is located at its intersection with State Route 10 to the east of downtown Greenville. From this point, the route travels in a northwesterly direction to its northern terminus at its intersection with State Route 185 to the north of downtown Greenville.

The entire route is in Greenville, Butler County.