State Route 207 or SR-207 is a 13.959-mile (22.465 km) long route that serves as a connection between U.S. Highway 72 in Rogersville in Lauderdale County and the Tennessee state line. After crossing the state line, this becomes Tennessee State Route 11.

The southern terminus of SR-207 is located at its intersection with U.S. Highway 72 in southern Rogersville. From this point, the route travels in a northerly direction towards Anderson. From Anderson, the route turns to the northeast before resuming a more northerly track after its junction with State Route 99 as it enters Tennessee.

The entire route is in Lauderdale County.