State Route 358 (SR 358, OH 358) is a 0.92-mile (1.48 km) long north–south state highway in the northern portion of the U.S. state of Ohio. The southern terminus of SR 358 is at a T-intersection with SR 163 nearly 5.75 miles (9.25 km) east of Oak Harbor, just north of the Portage River. Its northern terminus is at SR 2 at an intersection just outside of Camp Perry about 3.50 miles (5.63 km) west of Port Clinton.

This two-lane state highway was created in the middle of the 1930s. Throughout its history, the primary purpose of SR 358 has been to provide state highway access to Camp Perry. Today, it also provides access from SR 2 eastbound to SR 163, as well as from SR 163 to SR 2 westbound, as an interchange between the two routes approximately 1 mile (1.6 km) to the east does not allow for those connections. The entire length is SR 163 is a part of the Lake Erie Circle Tour.

SR 358 exists entirely within Erie Township in the central portion of Ottawa County. It begins at a T-intersection with SR 163 east of Oak Harbor, opposite the Port Clinton Golf Course, which is situated on the north banks of the Portage River. The highway crosses over the CSX railway, and passes by a mix of woods and fields on the short journey up to its endpoint at SR 2, along a multi-lane stretch of the major state route opposite of the main entrance into Camp Perry.

This state highway is not included as a part of the National Highway System (NHS). The NHS is a network of routes identified as being most important for the economy, mobility and defense of the nation.

SR 358 was applied in 1934. The highway has maintained the same brief routing through the central portion of Ottawa County throughout its lifetime. In addition, the entire length of SR 358 has been paved since its inception.

The entire route is in Erie Township, Ottawa County.